TB-500 5mg Research Overview
TB-500 5mg is offered by Ascension Peptides for qualified laboratory, analytical, and pre-clinical research use. The page is organized around product identity, research context, documentation, and related catalog navigation so researchers can evaluate the material without relying on unsupported human-use or medical claims.
Thymosin Beta-4 fragment, commonly designated as TB-500, represents a synthetic analogue of the active region derived from the naturally occurring thymosin beta-4 protein. The parent compound thymosin beta-4 is a 43-amino acid peptide with the sequence SDKPDMAEI EKFDKSKLKK TETQEKNPLP SKETIEQEKQ AGES, exhibiting a molecular weight of 4982 g/mol and an isoelectric point of 5.1. TB-500 specifically incorporates the actin-binding domain of thymosin beta-4, which plays a crucial role in regulating cellular structure and function through interaction with actin filaments. Research applications have demonstrated that TB-500 exhibits anti-fibrotic activity through inhibition of Akt signaling pathways, making it valuable for investigating cellular response mechanisms. The synthetic nature of TB-500 allows for consistent production and standardized research applications, with typical preparations available in 5mg concentrations for laboratory use.
Research Context and Product Evaluation
This material may be relevant to thymosin beta-derived peptide structure, actin-binding research and cellular signaling. Researchers should distinguish between biochemical or pre-clinical observations in the scientific literature and claims about human outcomes. Ascension Peptides supplies this product as a research material only; the listing is not intended to provide clinical guidance, dosing instructions, or therapeutic recommendations.
Before beginning an experiment, verify the product label, stated amount, lot or batch information, and any available analytical documentation. Researchers should also record the material used in each protocol so results can be traced back to the specific batch. Storage, preparation, and handling should follow the product documentation, the laboratory’s validated SOPs, and any requirements appropriate to the experimental method.
Quality and Analytical Documentation
Product quality should be assessed with evidence rather than marketing language alone. Where available, review the Certificates of Analysis and related analytical information for identity and purity data. Analytical results can vary by batch and method, so researchers should rely on the documentation associated with the material actually received rather than assuming that one report applies to every lot.
Ascension Peptides emphasizes clear product identification and research-only positioning across its catalog. Questions about a listing, documentation, or order details can be directed to customer support.
Related Peptides Research Products
For comparative laboratory work, researchers may also review BPC-157 5mg, BPC-157 10mg, and Wolverine Stack 20mg. These internal references are provided to make it easier to compare materials within the same research catalog rather than to imply that compounds are interchangeable.
Browse the broader Peptides collection for additional research materials in this category.
Research Use Only
This product is intended strictly for research, development, and analytical laboratory use by qualified professionals. It is not intended for human or veterinary consumption, use as a food additive, household use, or use to diagnose, treat, cure, or prevent any disease. Product information is provided for catalog identification and research context only.



